Table 2.
Immune subsets assessed by multiplex IHC
Marker expression | Panel | Cell subset | Abbreviation |
CD3+CD4+CD8- | T cell | T-helper | T-helper |
CD3+CD8+CD4- | T cell | CD8+ T cells | CD8+ T cells |
CD3+CD4+FOXP3+ | T cell | Regulatory T cell | Treg |
CD3+CD4-CD8- | T cell | Double negative T cell | DNT |
CD3+ | Pan immune | Pan T cell | T cell |
CD20+ | Pan immune | B cell | B cell |
CD68+ | Pan immune | Macrophage | φ |
CD68+CD11c+ | Pan immune | Dendritic cell | DC |
CD68+PDL1+ | Pan immune | PDL1+ macrophage | φPDL1+ |
CD68+CD11c+PDL1+ | Pan immune | PDL1+ dendritic cell | DC PDL1+ |
HMWCK+PDL1+ | Pan immune | PDL1+ basal cells | HMWCK+PDL1+ |
HMWCK-PDL1+ | Pan immune | PDL1+ nonbasal cells | HMWCK-PDL1+ |
IHC, immunohistochemistry.