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. 2020 Jun 25;8(1):e000491. doi: 10.1136/jitc-2019-000491

Figure 4.

Figure 4

Clustering of metastatic samples using immune-related datasets. (A) Heatmap showing the metastatic samples grouped by hierarchical clustering using the GSVA enrichment scores for 25 innate and adaptive immunity-related gene sets. Samples are clustered in three major groups defined as Low ImmuneCluster (LIC), Medium ImmuneCluster (MIC) and High ImmuneCluster (HIC). Color bars at the top of the graph labels the samples by the metastatic site, their primary tumor of origin and the ImmuneCluster. (B) Barplot of metastatic location percentage in each ImmuneCluster. MHC, major histocompatibility complex; NSCLC, non-small-cell lung cancer.