Table 2.
How Trichoscopy Could Guide Alopecia Treatment
| Trichoscopic Features | Meaning | Suggested Therapeutic Conduct |
|---|---|---|
| Black dots and flame hairs | Acute and severe insult in anagen phase | Intensify therapies such as scalp cooling or topical vasoconstrictors with the aim of protecting hair follicles as much as possible. |
| Pohl-Pinkus hairs | Damage occurred, but it was not difficult to completely interrupt the mitotic activity; the insult just reduced mitotic activity (hair shaft constrictions) | The exact identification of timing could enable us to intensify the use of scalp cooling or topical vasoconstrictors when the insult is more aggressive. |
| Numerous yellow dots | Follicles are protected by acute damage (kenogen phase) | Use scalp cooling or topical vasoconstrictors with caution (for example, reducing the time or the number of applications). It has been hypothesized that a delayed hypoxic insult could induce neogenesis of hair follicle stem cells [15]. Indiscriminate use of scalp cooling and vasoconstrictors could be harmful if other chemotherapy cycles are expected. |