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. 2020 Jun 29;10(3):e2020074. doi: 10.5826/dpc.1003a74

Table 2.

How Trichoscopy Could Guide Alopecia Treatment

Trichoscopic Features Meaning Suggested Therapeutic Conduct
Black dots and flame hairs Acute and severe insult in anagen phase Intensify therapies such as scalp cooling or topical vasoconstrictors with the aim of protecting hair follicles as much as possible.
Pohl-Pinkus hairs Damage occurred, but it was not difficult to completely interrupt the mitotic activity; the insult just reduced mitotic activity (hair shaft constrictions) The exact identification of timing could enable us to intensify the use of scalp cooling or topical vasoconstrictors when the insult is more aggressive.
Numerous yellow dots Follicles are protected by acute damage (kenogen phase) Use scalp cooling or topical vasoconstrictors with caution (for example, reducing the time or the number of applications).
It has been hypothesized that a delayed hypoxic insult could induce neogenesis of hair follicle stem cells [15]. Indiscriminate use of scalp cooling and vasoconstrictors could be harmful if other chemotherapy cycles are expected.