Table 1.
Collagen Alpha-3 (VI) Chain and Endotrophin Exist in Different Types of Cancer
| Type | Mouse/Human | COL6A3 Gene/Protein | Detection Sample (Human) | Location | Ref |
|---|---|---|---|---|---|
| Breast Cancer | Human | Gene | Cancer Tissue | – | [37] |
| Full length COL6A3 & C-terminal domain | Cancer Tissue | Near the vicinity of the adipocytes | [36] | ||
| ETP | Cancer Tissue and Cancer cells and Plasma | - | [31,33] | ||
| Ovarian Cancer | Human | Gene | Cancer Cells | Epithelial cells | [78,80] |
| Hepatocellular Carcinoma | Human | Gene | Cancer Tissue | - | [48,49] |
| Bladder Cancer | Human | Gene | Cancer Tissue and Cancer Cells | - | [39,40] |
| Glioblastoma | Human | Gene | Cancer Cells | - | [53] |
| Adamantinomatous Craniopharyngioma | Human | Gene | Cancer Tissue | - | [50] |
| Wilms Tumor | Human | Gene | Cancer Tissue | - | [90] |
| Colon Cancer | Human | Gene | Cancer Tissue | Tumor endothelium | [38] |
| Full length COL6A3 | Cancer Tissue | - | [40,62] | ||
| ETP | Cancer Tissue | - | [31,33] | ||
| Mouse Embryonic Fibroblasts | Mouse | Gene | Fibroblasts | - | [89] |
| Esophageal Cancer | Human | Gene | Cancer Tissue | Tumor endothelium | [38] |
| Gastric Cancer | Human | Gene | Cancer Tissue/Cancer Cells | - | [44,45] |
| Lung Cancer | Human | Gene | Cancer Tissue | Tumor endothelium | [38] |
| Pancreatic Ductal Adenocarcinoma | Human | Full length COL6A3 | Cancer Tissue | Desmoplastic stroma around the malignant ducts | [46,47] |
| Tenosynovial Giant Cell Tumors | Human | Gene | Cancer Tissue | - | [85,87] |
| Uterine Leiomyoma | Human | Gene | Cancer Tissue | - | [55] |
| Salivary Gland Carcinoma (Mucoepidermoid Carcinoma) | Human | Gene | Cancer Tissue | - | [51] |
| Prostate Cancer | Human | Gene | Cancer Tissue | - | [40,54] |
| Juvenile Angiofibroma | Human | Gene | Cancer Tissue | - | [52] |
Abbreviations: ETP, endotrophin; Ref, reference.