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. Author manuscript; available in PMC: 2020 Nov 11.
Published in final edited form as: Nature. 2020 May 11;582(7813):577–581. doi: 10.1038/s41586-020-2277-x

Extended Data Figure 5. Relationship of rs2105898 alleles to a known ZNF143 binding motif in the XL9 region of the MHC class II locus.

Extended Data Figure 5.

(a) Location of rs2105898 (yellow line at center) within the XL9 region, with relevant tracks showing overlapping histone marks and transcription factor binding peaks (from ENCODE52), visualized with the UCSC genome browser53.

(b) ZNF143 consensus binding motif as a sequence logo, with the letters colored if the base is present in >5% of observed instances. The alleles of rs2105898 are indicated by outlined box surrounding the base.