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. Author manuscript; available in PMC: 2021 Jul 15.
Published in final edited form as: Cancer. 2020 May 6;126(14):3289–3296. doi: 10.1002/cncr.32939

Table 3.

Screening mammography performance metrics based on initial vs. final assessment, among women with a recent screening mammogram in the Breast Cancer Surveillance Consortium, 2005–2017.

Initial Assessment Final Assessment
Screening Performance Metric Estimate 95% CI Estimate 95% CI
Standard performance measures
Cancer detection rate, per 1000 4.1 3.9, 4.3 4.1 3.8, 4.3
Interval cancer rate, per 1000 0.69 0.64, 0.74 0.77 0.71, 0.83
Sensitivity, % 85.7 84.8, 86.6 84.1 83.0, 85.1
Specificity, % 91.8 91.0, 92.4 97.4 97.0, 97.6

Screening benefit
Stage I or IIa screen-detected invasive cancers, per 1000 2.7 2.5, 2.8 2.6 2.5, 2.8

Screening false-alarms
False-positive recall for additional imaging, per 1000 82.1 75.3, 89.4 NA NA
False-positive short interval follow-up recommendation, per 1000 NA NA 16.5 13.9, 19.5
False-positive biopsy recommendation, per 1000 NA NA 9.8 8.5, 11.3

Screening failures
Stage IIb or higher interval invasive cancers, per 1000 0.16 0.15, 0.18 0.18 0.16, 0.20
Stage IIb or higher screen-detected invasive cancers, per 1000 0.29 0.26, 0.33 0.27 0.24, 0.31

CI, confidence interval; NA, not applicable.