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. 2020 Jun 26;10:10444. doi: 10.1038/s41598-020-67229-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Subcellular localization of LRPPRC following of PGC-1α overexpression. n = 4; visulization was performed using fluorescence confocal microscopy. (a) The immunofluorescence results of LRPPRC subcellular localization. Mitochondria for 647 channels of excitation light, appear in green; LRPPRC is 594 channels of excitation light, appearing in red; the nucleis are stained by DAPI and appear in blue. Note: Con (control group), M (MPP⁺ group), A + M (Ad+MPP⁺ group), A + Con (Ad+control group), P + Con (PGC-1α + control group), P + M (PGC-1α + MPP⁺ group). (b,c) The Pearson’s corrleation confficient of LRPPRC in mitochondria and nucleus. ns, no statistical significance; *P < 0.05 PGC-1α + MPP⁺ compared with MPP⁺.