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. 2020 Jun 26;10:10464. doi: 10.1038/s41598-020-67525-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of the potential of the three selected genes to differentiate TNBC from non-TNBC based on their expression pattern. (A) The TCGA provisional dataset (tcga_rnaseqV2_brca_v2.0_gene_sample) consisting of 1,101 patients and 1,108 samples was analyzed in cbioportal to see the difference in the expression level of the three selected genes (TBC1D9, SLC16A6 and MFGE8) in TNBC and non-TNBC patients. (B) mRNA expression of the selected genes in TNBC and non-TNBC patients. The first row shows the data from 877 patients from the dataset TCGA-BRCA (nationwidechildrens.org_clinical_patient_brca.txt), which consists of 140 TNBC and 737 non-TNBC patients. The second row is the expression in patients from our tissue repository (TNBC = 13; non-TNBC = 12). The statistical analysis score is the distribution of Wilcoxon rank sum test. **** = p value < 0.0001.