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. 2020 Jun 26;10:10479. doi: 10.1038/s41598-020-66633-2

Table 3.

Free testosterone levels in relation to genotypes in the PCOS group. Data are presented as the geometric means (95% CI). 9.56 × 10−1.

Nearest gene SNP Genotype n Free testosterone
(ng/dL)
P
FSHB rs11031006 GG 762 0.75 (−0.33, −0.26) 1.94 × 10−3
AA + AG 100 0.84 (−0.23, −0.04)
FSHR rs2268361 AA 205 0.72 (−0.29, −0.22) 0.060
GG + GA 657 0.77 (−0.29, −0.22)
LHCGR rs10176989 AA 602 0.78 (−0.40, −0.28) 6.90 × 10−3
CC + CA 260 0.71 (−0.028, −0.21)
TOX3 rs11075466 AA 337 0.75 (−0.34, −0.24) 0.50
GG + GA 525 0.77 (−0.31, −0.23)
RAB5B rs705704 GG 471 0.77 (−0.30, −0.22) 0.35
AA + GA 391 0.74 (−0.34, −0.25)
KHDRBS3 rs10505648 AA 767 0.75 (−0.31, −0.24) 0.62
GG + GA 95 0.80 (−0.35, −0.16)
YAP1 rs1894116 AA 551 0.77 (−0.30, −0.22) 0.19
GG + GA 311 0.74 (−0.36, −0.25)
THADA rs13429458 CC 335 0.78 (−0.43, −0.14) 0.12
AA + AC 518 0.74 (−0.31, −0.24)
DENDD1A rs2479106 AA 463 0.72 (−0.35, −0.27) 0.020
GG + GA 399 0.80 (−0.28, −0.19)
INSR rs2059807 AA 426 0.75 (−0.31, −0.22) 0.51
GG + GA 436 0.77 (−0.33, −0.24)
C9orf3 rs4385527 GG 554 0.76 (−0.31, −0.23) 0.62
AA + AG 305 0.77 (−0.34, −0.23)
SUMO1P1 rs6013809 CC 334 0.75 (−0.34, −0.24) 0.47
AA + AC 520 0.76 (−0.31, −0.23)

All results were adjusted for age and body mass index.

CI, confidence interval; PCOS, polycystic ovary syndrome; SNP, single nucleotide polymorphism.