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. 2020 May 16;57(7):2889–2901. doi: 10.1007/s12035-020-01928-z

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© The Author(s) 2020

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Fig. 2 — Kaplan–Meier overall survival curves in the adult GBM cohort (rim). a High expression of cytoplasmic TrxR is associated with poor overall survival (P = 0.027). No significant associations between nuclear TrxR (b), cytoplasmic/nuclear Trx (c/d) or TxNIP (e) expression and overall survival are observed (all P values > 0.05). Curves show low (blue line) and high protein expression (green line) with significance determined using the log-rank test. The numbers below the Kaplan–Meier curves are the number of patients at risk at the specified month