Table 1.
Clinical and histopathological parameters of the patients and influence on anastomotic leakage
| Patient characteristics | Number of patients (n = 38) | AL (n = 18) | Non-AL (n = 20) | p value |
|---|---|---|---|---|
| Tumor localization | ||||
| Colon | 14 (36.8%) | 3 (16.7%) | 11 (55%) | 0.014 |
| Rectum | 24 (63.2%) | 15 (83.3%) | 9 (45%) | |
| Median age | 0.492 | |||
| ≤ 60 years | 17 (44.7%) | 7 (38.9%) | 10 (50%) | |
| > 60 years | 21 (55.3%) | 11 (61.1%) | 10 (50%) | |
| Gender | 0.043 | |||
| Male | 28 (73.7%) | 16 (88.9%) | 12 (60%) | |
| Female | 10 (26.3%) | 2 (11.1%) | 8 (40%) | |
| BMI [kg/m2] | 0.587 | |||
| < 25 | 16 (42.1%) | 4 (22.2%) | 6 (30%) | |
| ≥ 25 | 22 (57.9%) | 14 (77.8%) | 14 (70%) | |
| Smoker | 0.463 | |||
| Yes | 27 (71%) | 6 (33.3%) | 9 (45%) | |
| No | 11 (29%) | 12 (66.7%) | 11 (55%) | |
| T category | 0.253 | |||
| T1 | 0 (0%) | 0 (0%) | 0 (0%) | |
| T2 | 7 (18.4%) | 4 (22.2%) | 3 (15%) | |
| T3 | 25 (65.8%) | 13 (72.2%) | 12 (60%) | |
| T4 | 6 (15.8%) | 1 (5.6%) | 5 (25%) | |
| N category | ||||
| N0 | 21 (55.2%) | 9 (50%) | 12 (60%) | 0.582 |
| N1 | 11 (29%) | 5 (27.8%) | 6 (30%) | |
| N2 | 6 (15.8%) | 4 (22.2%) | 2 (10%) | |
| M category | ||||
| M0 | 26 (68.4%) | 10 (55.6%) | 16 (80%) | |
| M1 | 12 (31.6%) | 8 (44.4%) | 4 (20%) | 0.106 |
| R | 0.485 | |||
| R0 | 35 (92.1%) | 16 (88.9%) | 19 (95%) | |
| R1 | 3 (7.9%) | 2 (11.1%) | 1 (5%) | |
| Grading | 0.085 | |||
| G1 | 0 (0%) | 0 (0%) | 0 (0%) | |
| G2 | 19 (50%) | 7 (38.9%) | 12 (60%) | |
| G3 | 5 (13.2%) | 4 (22.2%) | 1 (5%) | |
| n/a* | 14 (36.8%) | 7 (38.9%) | 7 (35%) | |
| Neoadjuvant therapy | 0.804 | |||
| Yes | 14 (36.8%) | 7 (38.9%) | 7 (35%) | |
| No | 24 (63.2%) | 11 (61.1%) | 13 (65%) | |
n/a not available; *due to neoadjuvant radiochemotherapy