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Changes in coagulation factor VIII activity level and APTT after recombinant factor VIII infusion. The x-axis shows the time from the end of the HD session. The y-axis shows the factor VIII activity level and APTT concentration. The factor VIII activity peaked 10 min after administration of recombinant factor VIII. ACT activated clotting time; APTT activated partial thromboplastin time; HD hemodialysis
