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. 2020 Jun 26;11:3222. doi: 10.1038/s41467-020-17017-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Schematic representation of the tripartite SC structure of mouse showing the two lateral elements (LEs) consisting of SYCP2 and SYCP3 flanking the central element composed of SYCE1/2/3, Tex12, and SIX6OS1. The transverse filament protein SYCP1 is connecting the lateral element and the central element with the SYCP1 C terminus residing in the lateral and the N terminus in the central element³². b Schematic representation of the helical structure of the SC exposing frontal view sections and lateral view sections. Lateral elements (SYCP3, SYCP2) in blue, central element (SYCE3-SYCE1, SIX6OS1, and SYCE2-TEX12) in green, transverse filaments (SYCP1) in purple in accordance with a. Individual transverse filaments are further marked with asterisks. The lateral elements are not displayed in the lateral view section to expose the central element and transverse filaments.