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. 2020 Jun 26;10:10465. doi: 10.1038/s41598-020-67342-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Immunocytochemical staining and propranolol plus docetaxel effectiveness in SFT primary cell models. (A) β-AR expression in SFT cells. Image scale bar, 100 µm. (B) SFT cells were incubated with docetaxel alone or in combination with propranolol for 72 h. The inhibition of cell proliferation, shown in the histogram, is the mean median of three experiments (mean ± SD, ***p < 0.001; *p < 0.05; where p values of single drugs were calculated with respect to Ctrl, while the p value of combination was calculated with respect to single drugs).