Figure 3. Risk Factors of Severe Coronavirus Disease 2019 (COVID-19).

Severe COVID-19 was defined as a severity score of 3 or more. A, Univariate analysis. B, Multivariate analysis. Results are expressed as odds ratios (ORs) with 95% CIs. C, Cumulative variability (McFadden R²) of severe COVID-19 accounted for each variable retained in the multiple logistic regression model. Numbers of patients per category: men, 98; with 1 or more comorbidity, 113; with obesity, 24; with cardiac comorbidity, 23; with an Expanded Disability Severity Status (EDSS) score less than 3, 194; with an EDSS of 3 to 5.5, 75; with an EDSS of 6 or more, 69; without disease-modifying therapy, 63; receiving interferon or glatiramer acetate, 53; receiving teriflunomide, dimethylfumarate, natalizumab, or other drugs, 130; and receiving fingolimod, ocrelizumab, rituximab, cladribine, or alemtuzumab, 101. NA indicates not applicable.