Table 2.
Treatment outcomes, median time, and rates of adverse treatment outcomes.
| Treatment outcome* | No. of events (%) | Median time of outcome, d (95% CI) | Rate of adverse outcomes per 100 person years at risk (95% CI) |
|---|---|---|---|
| Favorable outcome | 418 (81.9) | Cat I = 186 (184.4–187.6) | – |
| Cat II = 244 (240.1–247.9) | |||
| Cured | 178 (34.9) | Cat I = 193 (184.6–201.4) | – |
| Cat II = 252 (242.5–261.5) | |||
| Treatment completed | 240 (47.0) | Cat I = 184 (182.4–185.6) | – |
| Cat II = 241 (236.8–245.2) | |||
| Adverse treatment outcome | 85 (16.7) | 81 (56.4–105.6) | 32.60 (26.20–40.11) |
| Death | 29 (5.7) | 59 (41.4–76.6) | 16.88 (12.41–22.45) |
| Default | 44 (8.6) | 66 (55.2–76.8) | 11.12 (7.59–15.77) |
| Failure | 9 (1.8) | 237 (216.5–257.5) | 3.45 (1.68–6.34) |
| Shift to Category IV | 3 (0.6) | 118 (0–271.6) | 1.15 (0.29–3.13) |
Cat = category; CI = confidence interval.
Cured: Initially sputum smear-positive patient who has completed treatment and had negative sputum smears on two occasions, one of which was at the end of the treatment.
Treatment completed: Initially sputum smear-positive patient who has completed treatment with negative smears at end of the intensive phase/2 months in the continuation phase, but none at the end of the treatment is declared as treatment completed. Or extrapulmonary/initially sputum-negative patient who has received the full course of treatment and has not become smear positive at the end of the treatment.
Died: A patient who died during the course of the treatment, regardless of any cause.
Default: A patient after treatment initiation has interrupted treatment consecutively for >2 months.
Treatment failure: Any TB patient who is smear-positive at 5 months or more after initiation of the treatment and not put on multidrug resistance (MDR)-TB treatment.
Shift to Category IV: A patient who has been diagnosed as having MDR-TB by an RNTCP accredited laboratory, prior to being declared as “Failure”, and is placed on the RNTCP MDR-TB treatment regimen.
Relapse: A TB patient who was declared cured or treatment completed by a physician and who reports back to the health facility and is now found to be sputum smear positive.
Transferred out: A patient who has been transferred to another TU/district/state and whose treatment outcome is not available is considered as “Transferred Out” [1].