Table 1.
Summary of transport time and diagnostic results for the OMNIgene SPUTUM and standard of care methods.
| Sample ID | Days in transport | Smear | LJ culture: time to positive (d) | OMS impact on TTP (d) | Avg TTP SOC | Avg TTP OMS | Δ TTP for OMS | ||
|---|---|---|---|---|---|---|---|---|---|
| SOC | OMS | SOC | OMS | ||||||
| 4600 | 0 | 1+ | 1+ | 21 | 24 | 3 | 21 | 24 | 3 |
| 4796 | 0 | Neg | Neg | NG | NG | NG | |||
| 4820 | 0 | Neg | Neg | NG | NG | NG | |||
| 4547 | 0 | Neg | Neg | NG | NG | NG | |||
| 4582 | 0 | Neg | Neg | NG | NG | NG | |||
| 4649 | 0 | Neg | Neg | NG | NG | NG | |||
| 4671 | 0 | Neg | Neg | NG | NG | NG | |||
| 4661 | 0 | Neg | Neg | NG | NG | NG | |||
| 4817 | 0 | Neg | Neg | NG | NG | NG | |||
| 2081 | 2 | 2+ | 1+ | 17 | 23 | 6 | 17 | 21 | 4 |
| 2071 | 2 | 2+ | 1+ | 17 | 23 | 6 | |||
| 2336 | 2 | 3+ | 3+ | 16 | 16 | 0 | |||
| 2366 | 2 | 2+ | 2+ | 18 | 23 | 5 | |||
| 2374 | 2 | 1+ | Scanty | NG | NG | NG | |||
| 1966 | 3 | 2+ | 1+ | Contaminated | 28 | Rescued | 22 | 23 | 1 |
| 2064 | 3 | 1+ | Scanty | 25 | 25 | 0 | |||
| 2067 | 3 | 1+ | 3+ | 36 | 29 | −7 | |||
| 2068 | 3 | 1+ | 1+ | Contaminated/29 | 25 | −4 | |||
| 2093 | 3 | 1+ | 1+ | 6 | 19 | 13 | |||
| 2099 | 3 | 3+ | 2+ | 25 | 19 | −6 | |||
| 2114a | 3 | 2+ | 1+ | Contaminated | 23 | Rescued | |||
| 2186 | 3 | Neg | Neg | NG | NG | NG | |||
| 2200 | 3 | 3+ | 3+ | 12 | 18 | 6 | |||
| 2355 | 3 | Neg | Neg | Contaminated | NG | NG/Rescued | |||
| 2356 | 3 | Neg | Neg | NG | NG | NG | |||
| 2357 | 3 | Neg | Neg | NG | NG | NG | |||
| 2360 | 3 | Neg | Neg | NG | NG | NG | |||
| 2370 | 3 | Neg | Neg | NG | NG | NG | |||
| 2371a | 3 | Neg | Neg | NG | NG | NG | |||
| 2372 | 3 | 3+ | 3+ | 18 | 18 | 0 | |||
| 1872 | 4 | 2+ | 3+ | 16 | 23 | 7 | 22 | 22 | 0 |
| 1879 | 4 | 1+ | 1+ | Contaminated/NG | NG | NG | |||
| 1880 | 4 | 3+ | 3+ | 16 | 25 | 9 | |||
| 2054 | 4 | 3+ | 2+ | Contaminated | 34 | Rescued | |||
| 2060 | 4 | 3+ | 2+ | 18 | 18 | 0 | |||
| 2062 | 4 | 2+ | Scanty | 29 | 25 | −4 | |||
| 2075 | 4 | 2+ | 1+ | 29 | 18 | −11 | |||
| 2105 | 4 | 2+ | 2+ | Contaminated/23 | 17 | −6 | |||
| 2117 | 4 | 3+ | 1+ | Contaminated | 14 | Rescued | |||
| 2183 | 4 | Neg | Neg | NG | NG | NG | |||
| 1911 | 5 | 1+ | 1+ | 25 | 25 | 0 | 28 | 28 | 0 |
| 1929 | 5 | Scanty | Scanty | NG | NG | NG | |||
| 1941 | 5 | Neg | Neg | NG | NG | NG | |||
| 1945 | 5 | Neg | Scanty | 33 | 42 | 9 | |||
| 1946 | 5 | 1+ | 2+ | 41 | 41 | 0 | |||
| 2007 | 5 | 1+ | Scanty | 28 | 37 | 9 | |||
| 2014 | 5 | 3+ | 3+ | 25 | 21 | −4 | |||
| 2027 | 5 | 1+ | 1+ | 37 | 28 | −9 | |||
| 2034 | 5 | 1+ | Scanty | 21 | 25 | 4 | |||
| 2167 | 5 | 3+ | 3+ | 19 | 19 | 0 | |||
| 2165 | 5 | 3+ | 3+ | Contaminated | 19 | Rescued | |||
| 2326 | 5 | 1+ | 2+ | 25 | 20 | −5 | |||
| 1932 | 6 | Neg | Neg | NG | NG | NG | 19 | 18 | −1 |
| 2038 | 6 | 3+ | 3+ | 18 | 22 | 4 | |||
| 2287 | 6 | Scanty | Neg | NG | NG | NG | |||
| 2289 | 6 | 1+ | 2+ | 26 | Contaminated | Missed | |||
| 2292 | 6 | 3+ | 3+ | 14 | 17 | 3 | |||
| 2307 | 6 | 2+ | 1+ | 16 | 16 | 0 | |||
| 2181 | 7 | 1+ | 1+ | 21 | 21 | 0 | 21 | 21 | 0 |
| 2244 | 8 | 3+ | 3+ | Contaminated | 21 | Rescued | n/a | 21 | n/a |
Avg = average; d = days; LJ = Lowenstein–Jensen; Neg = negative; NG = no growth after 56 days; OMS = OMNIgene SPUTUM; SOC = standard of care; TTP = time to culture-positive; Δ TTP = difference in TTP between the methods.
a
Collected sample volume was 0.5 mL.