Fig. 1.

T-Gene link and score definitions. The picture shows a link that obeys the distance constraint d < D between the blue RE locus and the TSS. These links are output by T-Gene if they pass the significance threshold. The link between the red RE locus and the TSS does not obey the distance constraint but will be evaluated by T-Gene if it connects the RE locus to its closest TSS. Note that, the link on the left is also a ‘Closest-Locus’ link, and that a link may be a ‘Closest-TSS’ or ‘Closest-Locus’ link even if it obeys the distance threshold. If no histone/expression panel is provided, only the first and last scores are computed