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. 2020 Jun 27;1866(10):165889. doi: 10.1016/j.bbadis.2020.165889

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Fig. 4 — Genome of SARS-CoV2 originated in china: SARS-CoV2 (IVDC-HB-01/2019 (HB01) strain) RNA genome organization with pp1ab and pp1a proteins. The “orf1ab” is the largest gene, and it encodes for the “pp1ab” protein; contains nsp1-nsp10 and nsp12-nsp16 (15 nsps); another protein “pp1a” protein (coded by orf1a) contains nsp1-nsp10 (10 nsps). Structural proteins are encoded by the four structural genes, including spike (S), envelope (E), membrane (M), and nucleocapsid (N) genes. NSPS; non structural protein sequence, Orf; Open reading frame Credit: Adapted from Wu et al., Cell Host Microbe. 2020 Mar 11;27(3):325–328.