Table II.
Genes highly expressed in trophoblast derived from embryonic stem cells but not in cultured term trophoblast.
| Gene | hESC | hESCBAP <40 µm | hESCBAP >70 µm | primary human CTB | primary human STB |
|---|---|---|---|---|---|
| *GABRP | 1.3 | 1994.8 | 1074.2 | <0.1 | <0.1 |
| DIO3 | 5.8 | 248.5 | 1076.7 | 0.0 | 0.0 |
| NTRK2 | 0.1 | 142.0 | 99.1 | <0.1 | <0.1 |
| NDNF | 0.8 | 151.4 | 99.7 | <0.1 | 0 |
| CPE | 7.8 | 327.25 | 227.1 | .25 | 0.1 |
| *VTCN1 | 0.4 | 443.5 | 259.0 | 0.6 | 3.8 |
| MATN2 | 3.4 | 288.0 | 208.9 | 0.4 | 0.2 |
| *WFDC2 | 37.7 | 224.5 | 181.3 | 0.3 | 0.2 |
| IGFBPL1 | 21.3 | 123.1 | 111.5 | 0.25 | 0 |
| *ACTC1 | 56.2 | 388.2 | 273.9 | 0.8 | 0.2 |
| IGFBP5 | 1.4 | 275.1 | 195.6 | 0.7 | 0.2 |
| COL4A5 | 26.1 | 242.0 | 85.2 | 0.7 | 1.3 |
| NID2 | 8.2 | 237.6 | 136.3 | 0.7 | 0.6 |
| CTHRC1 | 2.7 | 286.5 | 180.7 | 0.8 | 0.6 |
| TNC | 9.0 | 299.5 | 180.3 | 0.9 | 1.2 |
| AADAT | 8.1 | 158.8 | 88.8 | 0.85 | 7.6 |
| PXDN | 57.8 | 100.2 | 99.6 | 0.6 | 0.3 |
| SESN3 | 28.3 | 134.1 | 77.1 | 0.9 | 1.2 |
| CGB8 | 0.2 | 102.1 | 1008.3 | 0.8 | 41.4 |
hESC, human embryonic stem cell; hESCBAP, hESC differentiated to TB with BAP.