Table 7.

Bayesian network analysis between high and low BMD subjects in “REACTOME_SIGNALING_BY_TGF_BETA.”

From–To (high BMD)	Strength	Direction	From–To (low BMD)	Strength	Direction
UBE2D3–UBE2D1	0.98	0.70	TGFBR2–SMAD7	0.82	0.73
UBE2D3–SMAD2	0.92	0.77	TGFBR1–SMURF2	0.80	0.55
UBE2D1–SMAD2	0.82	0.68
FURIN–SMURF2	0.88	0.80

Strength measures the significance of arcs between nodes (genes). Arcs are considered significant if they appear in at least 80% of the networks with bootstrap resampling to Bayesian network structures use for model averaging. Direction measures the direction of arcs learned by Bayesian network. Direction that appears most frequently (>0.5) is kept in the table.