Table 2.
Ranges of MIC50, MIC90 and Susceptible (%), Intermediate (%) and Resistant (%) Rates of Enterobacterales to Carbapenems and Colistin Between 2015 and 2017
| N | Range | MIC50 (mg/L) | MIC90 (mg/L) | S% | I% | R% | |
|---|---|---|---|---|---|---|---|
| All Enterobacterales | |||||||
| Colistin | 7113 | ≤ 1 to > 8 | ≤ 1 | > 4 | 87.7 | 0.0 | 12.3 |
| Ertapenem | 7113 | ≤ 0.03 to > 4 | ≤ 0.06 | > 4 | 83.6 | 3.0 | 13.4 |
| Imipenem | 7113 | ≤ 0.5 to > 32 | ≤ 0.5 | 8 | 83.2 | 5.1 | 11.7 |
| Meropenem | 4910 | ≤ 0.12 to > 16 | ≤ 0.12 | 16 | 88.0 | 0.4 | 11.6 |
| CR-Enterobacterales | |||||||
| Colistin | 1070 | ≤ 1 to > 8 | ≤ 1 | > 4 | 76.3 | 0.0 | 23.7 |
| Ertapenem | 1070 | ≤ 0.03 to > 4 | > 4 | > 4 | 10.7 | 0.5 | 88.9 |
| Imipenem | 1070 | ≤ 0.5 to > 32 | 32 | > 32 | 18.4 | 3.6 | 78.0 |
| Meropenem | 811 | ≤ 0.12 to > 16 | > 16 | > 16 | 27.9 | 2.2 | 69.9 |
| CS-Enterobacterales | |||||||
| Colistin | 5524 | ≤ 1 to > 8 | ≤ 1 | ≤ 1 | 92.9 | 0.0 | 7.1 |
| Ertapenem | 5524 | ≤ 0.03 to 0.5 | ≤ 0.06 | 0.25 | 100.0 | 0.0 | 0.0 |
| Imipenem | 5524 | ≤ 0.5 to 1 | ≤ 0.5 | 1 | 100.0 | 0.0 | 0.0 |
| Meropenem | 3765 | ≤ 0.12 to 1 | ≤ 0.12 | ≤ 0.12 | 100.0 | 0.0 | 0.0 |
| Escherichia coli | |||||||
| Colistin | 3657 | ≤ 1 to > 8 | ≤ 1 | ≤ 1 | 94.6 | 0.0 | 5.4 |
| Ertapenem | 3657 | ≤ 0.03 to > 4 | ≤ 0.06 | 0.5 | 90.6 | 2.7 | 6.7 |
| Imipenem | 3657 | ≤ 0.5 to > 32 | ≤ 0.5 | 1 | 94.8 | 1.4 | 3.9 |
| Meropenem | 2440 | ≤ 0.12 to >16 | ≤ 0.12 | ≤ 0.12 | 95.8 | 0.3 | 3.9 |
| CR-Escherichia coli | |||||||
| Colistin | 254 | ≤ 1 to > 8 | ≤ 1 | > 4 | 83.5 | 0.0 | 16.5 |
| Ertapenem | 254 | ≤ 0.03 to > 4 | > 4 | > 4 | 3.5 | 0.4 | 96.1 |
| Imipenem | 254 | ≤ 0.5 to > 32 | 4 | > 32 | 38.6 | 5.9 | 55.5 |
| Meropenem | 184 | ≤ 0.12 to > 16 | 4 | > 16 | 44.6 | 3.3 | 52.2 |
| CS-Escherichia coli | |||||||
| Colistin | 3273 | ≤ 1 to > 8 | ≤ 1 | ≤ 1 | 95.9 | 0.0 | 4.1 |
| Ertapenem | 3273 | ≤ 0.03 to 0.5 | ≤ 0.06 | 0.25 | 100.0 | 0.0 | 0.0 |
| Imipenem | 3273 | ≤ 0.5to 1 | ≤ 0.5 | ≤ 0.5 | 100.0 | 0.0 | 0.0 |
| Meropenem | 2181 | ≤ 0.12to 0.5 | ≤ 0.12 | ≤ 0.12 | 100.0 | 0.0 | 0.0 |
| Klebsiella pneumoniae | |||||||
| Colistin | 2150 | ≤ 1 to > 8 | ≤ 1 | 2 | 93.4 | 0.0 | 6.6 |
| Ertapenem | 2150 | ≤ 0.03 to > 4 | ≤ 0.06 | > 4 | 73.4 | 2.3 | 24.3 |
| Imipenem | 2150 | ≤ 0.5 to > 32 | ≤ 0.5 | > 32 | 75.6 | 2.7 | 21.7 |
| Meropenem | 1555 | ≤ 0.12 to >16 | ≤ 0.12 | > 16 | 75.9 | 0.6 | 23.5 |
| CR-Klebsiella pneumoniae | |||||||
| Colistin | 534 | ≤ 1 to > 8 | ≤ 1 | 4 | 88.6 | 0.0 | 11.4 |
| Ertapenem | 534 | ≤ 0.06 to > 4 | > 4 | > 4 | 1.9 | 0.4 | 97.8 |
| Imipenem | 534 | ≤ 0.5 to > 32 | > 32 | > 32 | 9.9 | 2.6 | 87.5 |
| Meropenem | 421 | ≤ 0.12 to > 16 | > 16 | > 16 | 11.2 | 2.1 | 86.7 |
| CS-Klebsiella pneumoniae | |||||||
| Colistin | 1529 | ≤ 1 to > 8 | ≤ 1 | ≤ 1 | 95.8 | 0.0 | 4.3 |
| Ertapenem | 1529 | ≤ 0.03to 0.5 | ≤ 0.06 | 0.25 | 100.0 | 0.0 | 0.0 |
| Imipenem | 1529 | ≤ 0.5 to 1 | ≤ 0.5 | 1 | 100.0 | 0.0 | 0.0 |
| Meropenem | 1072 | ≤ 0.12 to 1 | ≤ 0.12 | ≤ 0.12 | 100.0 | 0.0 | 0.0 |
| Enterobacter cloacae | |||||||
| Colistin | 407 | ≤ 1 to > 8 | ≤ 1 | > 4 | 73.5 | 0.0 | 26.5 |
| Ertapenem | 407 | ≤ 0.03 to > 4 | 0.12 | > 4 | 71.5 | 12.0 | 16.5 |
| Imipenem | 407 | ≤ 0.5 to > 32 | ≤ 0.5 | 8 | 82.6 | 6.6 | 10.8 |
| Meropenem | 272 | ≤ 0.12 to > 16 | ≤ 0.12 | 16 | 88.2 | 0.0 | 11.8 |
| CR-Enterobacter cloacae | |||||||
| Colistin | 72 | ≤ 1 to > 8 | ≤ 1 | > 4 | 79.2 | 0.0 | 20.8 |
| Ertapenem | 72 | ≤ 0.06 to > 4 | > 4 | > 4 | 6.9 | 0.0 | 93.1 |
| Imipenem | 72 | ≤ 0.5 to > 32 | 16 | > 32 | 31.9 | 6.9 | 61.1 |
| Meropenem | 49 | ≤ 0.12 to > 16 | 16 | > 16 | 34.7 | 0.0 | 65.3 |
| CS-Enterobacter cloacae | |||||||
| Colistin | 268 | ≤ 1 to > 8 | ≤ 1 | > 4 | 74.6 | 0.0 | 25.4 |
| Ertapenem | 268 | ≤ 0.03 to 0.5 | ≤ 0.06 | 0.5 | 100.0 | 0.0 | 0.0 |
| Imipenem | 268 | ≤ 0.5 to 1 | ≤ 0.5 | 1 | 100.0 | 0.0 | 0.0 |
| Meropenem | 185 | ≤ 0.12 to 0.25 | ≤ 0.12 | ≤ 0.12 | 100.0 | 0.0 | 0.0 |
| Klebsiella aerogenes | |||||||
| Colistin | 146 | ≤ 1 to > 8 | ≤ 1 | ≤ 1 | 92.5 | 0.0 | 7.5 |
| Ertapenem | 146 | ≤ 0.03 to > 4 | 0.25 | 2 | 87.0 | 2.1 | 11.0 |
| Imipenem | 146 | ≤ 0.5 to > 32 | 1 | 2 | 65.1 | 28.1 | 6.9 |
| Meropenem | 108 | ≤ 0.12 to > 16 | ≤ 0.12 | 0.25 | 94.4 | 0.0 | 5.6 |
| CR-Klebsiella aerogenes | |||||||
| Colistin | 16 | ≤ 1 to > 8 | ≤ 1 | > 8 | 87.5 | 0.0 | 12.5 |
| Ertapenem | 16 | 2 to > 4 | > 4 | > 4 | 0.0 | 0.0 | 100.0 |
| Imipenem | 16 | ≤ 0.5 to > 32 | 4 | > 32 | 37.5 | 0.0 | 62.5 |
| Meropenem | 11 | ≤ 0.12 to > 16 | 4 | > 16 | 45.5 | 0.0 | 54.6 |
| CS-Klebsiella aerogenes | |||||||
| Colistin | 86 | ≤ 1 to > 8 | ≤ 1 | 2 | 91.9 | 0.0 | 8.1 |
| Ertapenem | 86 | ≤ 0.03 to 0.5 | 0.25 | 0.5 | 100.0 | 0.0 | 0.0 |
| Imipenem | 86 | ≤ 0.5 to 1 | 1 | 1 | 100.0 | 0.0 | 0.0 |
| Meropenem | 65 | ≤ 0.12 to 0.25 | ≤ 0.12 | 0.25 | 100.0 | 0.0 | 0.0 |
Abbreviations: CS, carbapenem sensitive; CR, carbapenem-resistant; MIC, minimum inhibitory concentration; S, susceptibility; I, intermediate; R, resistance.