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Change from baseline in DAS scores of the principal therapeutic target domain for incobotulinumtoxinA versus placebo at week 4 of the MP. ** p ≤ 0.01. ANCOVA of change in DAS score from baseline to week 4 (incobotulinumtoxinA 400 U, n = 44; incobotulinumtoxinA 250 U, n = 23). DAS disability assessment scale, LS least squares, MP main period, SE standard error
