Table 3.
Adherence to study interventions based on weekly caregiver reports
| Adherence to supplementation* | TZ | PZ | MNP | CONTROL | P value |
|---|---|---|---|---|---|
|
N children |
848 |
844 |
841 |
847 |
|
|
Preventive† | |||||
| Total preventive tablets/sachets used, n (%) |
183 762 (92.4) |
179 299 (92.1) |
166 009 (89.2) |
178 116 (91.0) |
<0.001 |
|
Therapeutic | |||||
| Total therapeutic tablets given, n |
8124 |
7972 |
7449 |
7962 |
0.46 |
| Total number of diarrhea episodes reported |
1128 |
1095 |
1091 |
1157 |
|
| Days therapeutic tablet given per episode‡ |
6.8 ± 4.3 |
6.6 ± 3.9 |
6.2 ± 4.0 |
6.8 ± 4.7 |
0.10 |
| Episodes treated (%)§ |
982 (87) |
949 (87) |
953 (87) |
999 (86) |
0.902 |
| Tablet given within 10 days of initiation of treatment, n (%) |
6177 (76) |
6080 (76) |
5842 (78) |
6188 (77) |
<0.01 |
| Tablets given per treated episode |
6.2 ± 3.0 |
6.2 ± 3.1 |
5.9 ± 3.3 |
6.2 ± 3.0 |
0.22 |
| Days ORS used |
2487 |
2705 |
2618 |
2651 |
0.47 |
| Days ORS used per episode |
0.64 ± 0.7 |
0.62 ± 0.7 |
0.63 ± 0.7 |
0.65 ± 0.7 |
0.95 |
| Days treated with therapeutic tablet among children who never had diarrhea | 787 | 804 | 717 | 732 | 0.73 |
TZ – therapeutic zinc, PZ – preventive zinc, MNP –micronutrient powder, ORS – oral rehydration salt
*Excluded days for which the status of supplement intake was unknown.
†Adherence to preventive supplement defined as percentage of total observation days for which daily preventive supplement was given to the child.
‡The “days therapeutic tablet given per episode” include the total number of days the child took the therapeutic tablet regardless of whether or not is was given in relation to a diarrhea episode.
§A treat episode is defined as initiation of treatment (ie, consumption of the first tablet) within 7 days of the onset of diarrhea.