Table 1.

Association constant and Hill coefficient determined by the nonlinear fit of the titration data to Hill equation.

	Association Constant (Ka, × 104 M−1)	Hill Coefficient (n)
D1 ≅ H1	3.58 ± 0.09	1.41 ± 0.04
D1 ≅ H1endo	30.39 ± 2.49	1.74 ± 0.18
D1 ≅ H1exo	9.96 ± 0.16; 5.15 ± 0.08	8.00 ± 1.16; 4.03 ± 0.52
D1 ≅ H1external	0.84 ± 0.04	2.46 ± 0.09
D2 ≅ H1	6.69 ± 0.11	2.30 ± 0.09
D2 ≅ H1endo	28.08 ± 5.84	1.43 ± 0.28
D2 ≅ H1exo	5.90 ± 0.14	3.90 ± 0.41
D2 ≅ H1external	1.69 ± 0.04	3.61 ± 0.59
D1 ≅ H2	4.11 ± 0.15	1.99 ± 0.09
D2 ≅ H2	5.55 ± 0.13	1.60 ± 0.03