Table 3.
Biosynthetic gene clusters identified through antiSMASH analysis harboring a terpene cyclase.
No. | Gene Cluster | Size (bp) | Location | Terpene Cyclase | Associated Biosynthesis 1 |
---|---|---|---|---|---|
1 | Terpene | 27920 | 653776–674051 | 1 × Type I, 2 × Type II | This study |
2 | Terpene | 42274 | 1269631–1311904 | 1 × Type I | Geosmin [36,37] |
3 | Terpene | 41089 | 3415277–3456365 | 1 × Type I | Genome-Metab |
4 | Terpene | 41071 | 3447909–3488979 | 1 × Type I | |
5 | Terpene | 40978 | 3603511–3644488 | 1 × Type I | Genome-Metab |
6 | Terpene | 41041 | 4852259–4893299 | 1 × Type I | Genome-Metab |
7 | Terpene/Type_III_PKS | 69038 | 7156603–7225640 | 1 × Type II | Carotenoid [38,39,40,41] |
8 | Terpene/TfuA-rel. | 50108 | 8404785–8454892 | 1 × Type I | |
9 | Terpene/RiPP | 78053 | 12603875–12681927 | 1 × Type I | Geosmin [36,37] |
1 Genome-Metab.; these gene clusters have been excluded to be responsible for the formation of 1 and 2, due to the genome–metabolome correlation (myxobacterial strains with homologues BGCs featured no detectable production of 1 or 2, see SI).