Table 4.
Predicted functions of the proteins encoded by the (2-hydroxy)sorangiadenosine biosynthetic gene cluster.
| Gene | Size (aa) | Proposed Function | Closest Homologue | Coverage/Similarity (%) |
|---|---|---|---|---|
| sora1 | 378 | Oxidoreductase | WP_108075222 | 100/95.99 |
| sora2 | 72 | Hypothetical protein | WP_108075223 | 100/93.90 |
| sora3 | 173 | Hypothetical protein | WP_108075224 | 100/82.92 |
| sora4 | 364 | Methionine synthase (MetE) | WP_108075225 | 100/95.87 |
| sora5 | 304 | Hydrolase | WP_108075226 | 100/90.43 |
| sora6 | 284 | Hypothetical protein | WP_108075227 | 95/92.25 |
| sora7 | 457 | Cytochrome P450 enzyme | WP_108069092 | 98/95.67 |
| sora8 | 518 | Eudesmadiene transferase | WP_047856205 | 99/80.31 |
| sora9 | 333 | Terpene cyclase | WP_073564250 | 99.78/79.09 |
| sora10 | 387 | Hypothetical protein | WP_095976240 | 91/56.91 |
| sora11 | 609 | Sensory transducer | WP_146210122 | 92/74.69 |
| sora12 | 509 | Eudesmadiene transferase | WP_108075230 | 100/73.80 |
| sora13 | 1171 | Methionine synthase (MetH) | WP_108075232 | 100/97.61 |
| sora14 | 299 | SAM-dependent methyltransferase | WP_108075233 | 100/97.32 |
| sora15 | 292 | Patatin lipid acyl hydrolases | WP_108075234 | 100/98.97 |
| sora16 | 375 | Dehydrogenase | WP_052519033 | 91/82.11 |
| sora17 | 205 | TetR transcriptional regulator | WP_073564266 | 100/79.62 |
| sora18 | 147 | O-acetylhomoserine sulfhydrylase | WP_108075236 | 100/97.26 |
| sora19 | 302 | Hypothetical protein | WP_108075237 | 100/88.70 |
| sora20 | 449 | Thioredoxin | WP_140874099 | 99/54.81 |
| sora21 | 279 | Hypothetical protein | WP_158079939 | 100/77.34 |
| sora22 | 630 | Phosphotransferase | WP_073564278 | 100/79.83 |