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Efficacy and combinatory index (CI) of FA/5-FU (FF) and FF/OX/SN in CRC cells.
| Drug | DLD1 | HCT116 | SW620 | LS174T |
|---|---|---|---|---|
| FA [µM] 5-FU [µM] |
0.5 2.0 |
0.5 2.0 |
0.25 6.0 |
0.5 6.0 |
| ATP levels [% CTRL] ±SD |
83.2 2.1 |
83.4 3.8 |
91.5 4.5 |
86.6 4.9 |
| CI FF | 1.65 | 0.97 | 0.62 | 0.82 |
