Figure 2.
Examples of chemical modifications of nucleic acid analogs: 2′-substitutions (2′-O-methyl, and 2′-fluoro); locked nucleic acid modification (LNA); 5′-phosphorothioate (PS).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.