Table 3.
Compound | Solubility (mg/mL) | Melting Point (°C) | Melting Point Conformers (°C) |
---|---|---|---|
ADA | 1.03 | 206–208 | - |
ADA∙HCl | 50 | 300 | - |
ADA:OXA (I) | 0.81 | 223 | 189–191 |
ADA:GLUTA (II) | 58.8 | 183 | 95–98 |
ADA:METHA (V) | 200 | 153.9 a | 17–19 |
ADA:SAC (VI) | 14.3 | 242.6 | 228 |
ADA:SULFA (VII) | 5.6 | 347.3 a | 288 |
ADA:3-AMINO (VIII) | 9.1 | 244.2 | 178–180 |
ADA:4-AMINO (IX) | 0.96 | 245.9 | 187–189 |
a Melting point determined by the glass capillary method and by DSC-TGA.