Table 1.
Influence of ischemia/reperfusion-induced acute pancreatitis (IR-AP) and pretreatment with warfarin given at the dose of 90, 180 or 270 μg/kg/day, applied alone or in their combination (warfarin plus IR-AP) on morphological signs of pancreatic damage.
| Edema (0–3) | Inflammatory infiltration (0–3) | Vacuolization (0–3) | Necrosis (0–3) | Hemorrhages (0–3) | |
|---|---|---|---|---|---|
| Control | 0 | 0 | 0 | 0 | 0 |
| IR-AP | 2 | 2 | 0–1 | 1 | 1–2 |
| Warfarin 90 | 0–1 | 0 | 0 | 0 | 0 |
| Warfarin 180 | 0–1 | 0 | 0 | 0 | 0 |
| Warfarin 270 | 0–1 | 0 | 0 | 0 | 0–1 |
| Warfarin 90 + IR-AP | 1–2 | 1 | 0 | 1 | 1 |
| Warfarin 180 + IR-AP | 1–2 | 1 | 0 | 0–1 | 1 |
| Warfarin 270 + IR-AP | 2–3 | 2 | 1 | 1 | 2 |
Numbers represent the predominant histological grading in each group.