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Selectivity index of Cyperus articulatus rhizome essential oil (EO).
| Cancer Cells | Non-Cancerous Cells | ||
|---|---|---|---|
| MRC-5 | |||
| EO | DOX | 5-FU | |
| HepG2 | 1.6 | 69.7 | 37.5 |
| HCT116 | n.d. | 16.1 | 15 |
| MCF-7 | 1.3 | 7.5 | 4.2 |
| HL-60 | 1.4 | 52.3 | 4.7 |
| B16-F10 | 1.2 | 11.0 | 15 |
The data are presented as the selectivity index (SI) calculated using the following formula: SI = IC50 (non-cancerous cells)/IC50 (cancer cells). Doxorubicin (DOX) and 5-fluorouracil (5-FU) were used as positive controls. n.d. = not determined.
