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. 2020 Jun 25;8:e9437. doi: 10.7717/peerj.9437

Table 4. Identification of clinical parameters related to patient prognosis.

Variables Univariate analysis Multivariable analysis
HR 95% CI of HR P value HR 95% CI of HR P value
Entire TCGA cohort
Risk score (High/Low) 6.395 3.621–11.29 1.59E−10 5.356 2.970–9.658 2.42E−08
Age 1.036 1.019–1.053 1.61E−05 1.025 1.007–1.042 0.005
Gender (Male/Female) 1.001 0.637–1.574 0.994 0.751 0.462–1.219 0.246
FAB (M0–M3 vs M4–M7) 1.658 1.041–2.644 0.034 0.986 0.595–1.635 0.957
Bone marrow 0.997 0.986–1.009 0.679 1.004 0.992–1.016 0.512
White bloodcell count 1.005 0.999–1.011 0.05 1.006 1.001–1.012 0.03
GSE12417 cohort
Risk score (High/Low) 2.467 1.284–4.737 6.70E−03 2.458 1.273–4.746 7.40E−03
Age 1.031 1.004–1.059 0.022 1.03 1.004–1.056 0.022
FAB (M0–M3 vs M4–M7) 0.733 0.337–1.593 0.432 0.679 0.310–1.488 0.334
GSE37642 cohort
Risk score (High/Low) 1.457 0.951–2.232 8.40E−02 1.443 0.937–2.223 9.60E−02
Age 1.021 1.005–1.037 0.0073 1.02 1.005–1.035 0.01
FAB (M0–M3 vs M4–M7) 0.928 0.575–1.499 0.762 0.904 0.559–1.463 0.681