Table 4. Identification of clinical parameters related to patient prognosis.
Variables | Univariate analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI of HR | P value | HR | 95% CI of HR | P value | |
Entire TCGA cohort | ||||||
Risk score (High/Low) | 6.395 | 3.621–11.29 | 1.59E−10 | 5.356 | 2.970–9.658 | 2.42E−08 |
Age | 1.036 | 1.019–1.053 | 1.61E−05 | 1.025 | 1.007–1.042 | 0.005 |
Gender (Male/Female) | 1.001 | 0.637–1.574 | 0.994 | 0.751 | 0.462–1.219 | 0.246 |
FAB (M0–M3 vs M4–M7) | 1.658 | 1.041–2.644 | 0.034 | 0.986 | 0.595–1.635 | 0.957 |
Bone marrow | 0.997 | 0.986–1.009 | 0.679 | 1.004 | 0.992–1.016 | 0.512 |
White bloodcell count | 1.005 | 0.999–1.011 | 0.05 | 1.006 | 1.001–1.012 | 0.03 |
GSE12417 cohort | ||||||
Risk score (High/Low) | 2.467 | 1.284–4.737 | 6.70E−03 | 2.458 | 1.273–4.746 | 7.40E−03 |
Age | 1.031 | 1.004–1.059 | 0.022 | 1.03 | 1.004–1.056 | 0.022 |
FAB (M0–M3 vs M4–M7) | 0.733 | 0.337–1.593 | 0.432 | 0.679 | 0.310–1.488 | 0.334 |
GSE37642 cohort | ||||||
Risk score (High/Low) | 1.457 | 0.951–2.232 | 8.40E−02 | 1.443 | 0.937–2.223 | 9.60E−02 |
Age | 1.021 | 1.005–1.037 | 0.0073 | 1.02 | 1.005–1.035 | 0.01 |
FAB (M0–M3 vs M4–M7) | 0.928 | 0.575–1.499 | 0.762 | 0.904 | 0.559–1.463 | 0.681 |