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. 2020 Jun 24;15:4573–4589. doi: 10.2147/IJN.S255170

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© 2020 Piktel et al.

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Improvement of hemocompatibility of ceragenin CSA-131 when attached to MNP surface. Hemoglobin released from red blood cells incubated in the presence of CSA-131 (grey squares), MNP@CSA-131 (red circles) and CSA-131+MNP (blue diamonds) at concentrations ranging from 0 to 50 µg/mL (A). Minimal concentrations of CSA-131 (grey bar), MNP@CSA-131 (red bar) and CSA-131+MNP (blue bar) required to induce hemolysis in 10% of RBCs (B). Results are presented as mean ± SD from 3 to 6 individual experiments. ^Indicates statistical significance (p-value <0.05) when comparing to CSA131-treated cells.