Table 3. Hippocampal shrinkage rates by hemisphere and diagnoses at baseline and follow-up.

	Diagnosis at Baseline		Diagnosis at Follow-up
Hippocampal Contraction ml/year	Left	Right	Left	Right
Normal (N)	0.0115 ± 0.0004 (78)	0.0107 ± 0.0004 (78)	0.0124 ± 0.0004 (69)	0.0108 ± 0.0004 (69)
AD (N)	-	-	0.015# ± 0.002 (7)	0.019# ± 0.002 (7)
MCI (N)	0.020** ± 0.002 (6)	0.020** ± 0.001 (6)	0.016# ± 0.001 (8)	0.010 ±0.001 (8)
Results in Model**
Gender	T = −1.23/p = 0.22	T = −2.27/p = 0.03	T = 2.38/p = 0.02	T = −1.93/p = 0.06
Gender x Diagnosis	T = 1.65/p = 0.10	T = 2.67/p = 0.01	F = 7.8/ p = 0.001	F = 4.79/p = 0.01
Total dv-negative rate	T = 5.81/p < 0.0001	T=5.51/p<0.0001	F=7.1/ p=0.01	F=24.6/ p<0.0001
Diagnosis	T = −4.84/p < 0001	T =−5.17/ p < 0.0001	F = 5.7/ p = 0.005	F = 10.9/ p < 0.0001

x: post-hoc p-value < 0.0001; #post-hoc p-value < 0.05; ** Age, interscan interval, education, and TIV were not significant in the model.