Table 4A. Hippocampal volumes at baseline and at repeat scan (baseline + 5.8 years) for subjects classified using the baseline diagnosis (78 normal controls and 6 MCI). Adjustment variables age, interscan interval, gender, gender by diagnosis, and total GM volume, and education were not significant in the model (between subjects). Within subjects, only the time x diagnosis effect was significant.

	Hippocampal Volume
Hippocampal Volume, ml	Left	Right
Normal
Baseline	2.26 ± 0.02	2.72 ± 0.02
Repeat	2.23 ± 0.02	2.70 ± 0.02
MCI
Baseline	2.20 ±0.02	2.72 ± 0.02
Repeat	2.05 ±0.03	2.55 ± 0.03
Results in Model
Between Subjects
TIV	F = 23.9/p < 0.0001	F = 27.7/p < 0.0001
Within Subjects
Time x diagnosis	F = 12.0/p = 0.0009	F = 9.9/0.002

x: post-hoc p-value < 0.0001.