Fig. 7.

(A) Representative H&E stained histological images of bone formation in i) gel, ii) BP gel, and iii) BP-Bioglass (BG) nanocomposite gel. Vascularized bone formed abundantly inside the defect of osteoporotic rats due to the angiogenic effect of bioactive glass. (B) Images of wounds after BP-Ag nanocomposite hydrogel filled into wounds defect on day 0, day 3, day 6, day 10. The BP–Ag nanocomposite hydrogel displayed antimicrobial activities to both Gram-positive and Gram-negative microorganisms due to the antibacterial properties of silver, which prevents infections in wound healing. Reproduced with permission from Ref. [90], copyright 2017, John Wiley and Sons. Reproduced with permission from Refs. [91], copyright 2018, John Wiley and Sons.