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Involvement of circRNAs in Coronary Artery Disease (CAD)
Some circRNAs improve the pathological outcome of ischemia by promoting angiogenesis, cell proliferation, and migration. Other circRNAs, however, accelerate apoptosis, autophagy, and myocardial fibrosis, thus worsening the outcome of CAD. Some circRNAs are responsible for maintaining homeostasis in CAD by regulating inflammatory and stress responses.
