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Anti-prion systems in yeast
| Anti-prion protein | Target priori | Action | Mechanism | Ref. |
|---|---|---|---|---|
| Btn2p | [URE3] | curing | Sequester amyloid | (23, 31) |
| Cur1p | [URE3] | curing | unkown | (23, 31) |
| Ssb1,2p | [PSI+] | block generation | assist proper folding | (64, 91) |
| Sis1p | [PSI+] | block lethality | unknown | (71) |
| Hsp104p | [PSI+] | curing | controversial | (47) |
| Siw14p | [PSI+] | curing | lowering inositol 5-pyrophosphates | (48) |
| Upf1,2,3p | [PSI+] | curing | binding Sup35p or blocking amyloid elongation | (56) |
