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. Author manuscript; available in PMC: 2020 Jun 29.
Published in final edited form as: J Neuroimaging. 2020 Feb 10;30(3):297–302. doi: 10.1111/jon.12694

Table 2.

Mean Systolic Velocities, Pulsatility Indices, and HITs by Device

Waveform Parameters n MFV cm/second of MCA P Value MCA PI P Value Mean HITS/minute P Value
Preimplantation baseline 20 50.86 (12.31) .9 1.05 (.56) .5 .01 (.05) .3
VA-ECMO 27 56.07 (21) .7 .43 (.25) <.01** 2.81 (.09) .04*
HVAD 21 48.94 (15.93) .2 .35 (.17) <.01** .00 (.01) .3
HMII 5 57.30 (12.9) .8 .32 (.13) <.01** .02 (.06) .4
Tandem heart 3 33.25 (9.36) .03* .38 (.025) <.01* 1.07 (1.51) .5
TAH 25 79.69 (32.33) .2 .74 (.14) .5 12.55(12.04) .02*
Impella 13 53.72 (11.74) .2 .65 (.24) .07 8 (27) .02*
IABP 7 59.79 (11.54) .7 1.01 (.16) .7 .01 (.03) .4
HT 10 56.11 (16.39) 1.12 (.52) 0(0)

Note: Numbers are reported as mean (standard deviation) unless otherwise specified. P value is obtained from comparisons to HT studies.

*

P < .05

**

P < .01.

FiO2 = fraction inspired oxygen; HITS/min = high-intensity transient signal observed per minute; HMII = Heartmate II; HT = heart transplantation; HVAD = HeartWare ventricular assist device; IABP = intra-arterial balloon pump; MCA = middle cerebral artery; MFV = mean flow velocity; n = number of transcranial Doppler studies for each device; PI = pulsatility index; TAH, total artificial heart; VA-ECMO = venoarterial-extracorporeal membrane oxygenation.