Table 2.
Waveform Parameters | n | MFV cm/second of MCA | P Value | MCA PI | P Value | Mean HITS/minute | P Value |
---|---|---|---|---|---|---|---|
Preimplantation baseline | 20 | 50.86 (12.31) | .9 | 1.05 (.56) | .5 | .01 (.05) | .3 |
VA-ECMO | 27 | 56.07 (21) | .7 | .43 (.25) | <.01** | 2.81 (.09) | .04* |
HVAD | 21 | 48.94 (15.93) | .2 | .35 (.17) | <.01** | .00 (.01) | .3 |
HMII | 5 | 57.30 (12.9) | .8 | .32 (.13) | <.01** | .02 (.06) | .4 |
Tandem heart | 3 | 33.25 (9.36) | .03* | .38 (.025) | <.01* | 1.07 (1.51) | .5 |
TAH | 25 | 79.69 (32.33) | .2 | .74 (.14) | .5 | 12.55(12.04) | .02* |
Impella | 13 | 53.72 (11.74) | .2 | .65 (.24) | .07 | 8 (27) | .02* |
IABP | 7 | 59.79 (11.54) | .7 | 1.01 (.16) | .7 | .01 (.03) | .4 |
HT | 10 | 56.11 (16.39) | 1.12 (.52) | 0(0) |
Note: Numbers are reported as mean (standard deviation) unless otherwise specified. P value is obtained from comparisons to HT studies.
P < .05
P < .01.
FiO2 = fraction inspired oxygen; HITS/min = high-intensity transient signal observed per minute; HMII = Heartmate II; HT = heart transplantation; HVAD = HeartWare ventricular assist device; IABP = intra-arterial balloon pump; MCA = middle cerebral artery; MFV = mean flow velocity; n = number of transcranial Doppler studies for each device; PI = pulsatility index; TAH, total artificial heart; VA-ECMO = venoarterial-extracorporeal membrane oxygenation.