Table 2.

Association of left atrial structure and function and the analysed endpoints

	Unadjusted				Adjusted
	n	Events/person-years at risk	HR (95% CI)	P-value	n	Events/person-years at risk	HR (95% CI)	P-value
HF hospitalization or CV death (n = 142)
LAVi, per SD	971	142/2338	1.34 (1.17–1.52)	<0.001	776	103/1888	1.17 (0.96–1.41)	0.10
LAEF, per decrease SD	969	142/2333	1.41 (1.19–1.66)	<0.001	776	103/1888	1.35 (1.09–1.67)	0.005
LAEi, per decrease SD	969	142/2333	1.40 (1.16–1.68)	<0.001	776	103/1888	1.34 (1.06–1.69)	0.012
HF hospitalization (n = 93)
LAVi, per SD	965	93/2338	1.32 (1.12–1.55)	<0.001	776	69/1888	1.13 (0.88–1.44)	0.31
LAEF, per decrease SD	969	93/2333	1.42 (1.15–1.75)	0.001	776	69/1888	1.43 (1.10–1.85)	0.006
LAEi, per decrease SD	969	93/2333	1.44 (1.14–1.81)	0.002	776	69/1888	1.48 (1.11–1.99)	0.007
CV death (n = 64)
LAVi, per SD	971	64/2462	1.36 (1.13–1.65)	0.001	776	44/1983	1.22 (0.93–1.60)	0.14
LAEF, per decrease SD	969	64/2457	1.41 (1.10–1.81)	0.006	776	44/1983	1.33 (0.96–1.85)	0.08
LAEi, per decrease SD	969	64/2457	1.38 (1.05–1.82)	0.018	776	44/1983	1.26 (0.88–1.79)	0.19

Adjustment for: age, sex, diabetes, heart rate, history of heart failure (HF), history of myocardial revascularization, atrial fibrillation pattern, allocated therapy, left ventricular (LV) end-diastolic volume index, LV ejection fraction, LV mass index and E/e′. CI, confidence interval; CV, cardiovascular; HR, hazard ratio; LAEF, left atrial emptying fraction; LAEi, left atrial expansion index; LAVi, left atrial volume index by body surface area; SD, standard deviation.