. Author manuscript; available in PMC: 2020 Jun 29.

Published in final edited form as: Am J Kidney Dis. 2016 Dec 23;69(3):410–419. doi: 10.1053/j.ajkd.2016.10.019

Table 2.

Spearman Correlation Matrix of Urine Fibrosis Markers, eGFR, Urine ACR, and Urine Injury Biomarkers in FAVORIT

	A1M/Cr	MCP-1/Cr	PIIINP/Cr	PINP/Cr	eGFR	ACR	NGAL/Cr	IL-18/Cr	KIM-1/Cr	L-FABP/Cr

A1M/Cr	1.000
MCP-1/Cr	0.292^a	1.000
PIIINP/Cr	0.641^a	0.134^a	1.000
PINP/Cr	0.407^a	0.138^a	0.465^a	1.000
eGFR	−0.250^a`	−0.099^a	−0.080	−0.096^a	1.000
ACR	0.508^a	0.475^a	0.304^a	0.214^a	−0.211^a	1.000
NGAL/Cr	0.395^a	0.293^a	0.332^a	0.305^a	−0.234^a	0.343^a	1.000
IL-18/Cr	0.297^a	0.170^a	0.194^a	0.146^a	−0.011	0.242^a	0.382^a	1.000
KIM-1/Cr	0.113^b	0.554^a	−0.024	−0.013	−0.052	0.319^a	0.243^a	0.157^a	1.000
L-FABP/Cr	0.768^a	0.361^a	0.495^a	0.302^a	−0.257^a	0.593^a	0.413^a	0.317^a	0.212^a	1.000

Note:Spearman correlation matrix is limited to persons sampled within the subcohort. All urine measures are indexed to urine creatinine.

Abbreviations: A1M, α₁-microglobulin; ACR, albumin-creatinine ratio; Cr, creatinine; eGFR, estimated glomerular filtration rate; FAVORIT, Folic Acid for Vascular Outcome Reduction in Transplantation; NGAL, neutrophil gelatinase-associated lipocalin; KIM-1, kidney injury molecule 1; IL-18, interleukin 18; L-FABP, liver-type fatty acid binding protein; MCP-1, monocyte chemoattractant protein 1; PINP, procollagen type I; PIIINP, procollagen type III.

P,< 0.01.

P ,< 0.05.