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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Pediatr. 2020 May 13;222:112–119.e3. doi: 10.1016/j.jpeds.2020.02.023

Table I.

Maternal and fetal/infant ZIKV testing results among cases of microcephaly and/or CNS defects, Colombia, September 2015-April 2017 (n = 858)

Laboratory findings consistent with possible ZIKV infection in a maternal specimen* Laboratory findings consistent with possible ZIKV infection in a fetal/infant specimen Reported cases, n (%)
Yes Yes 52 (6.1)
Yes No 17 (2.0)
Yes Not tested 103 (12.0)
No Yes 19 (2.2)
No No 42 (4.9)
No Not tested 31 (3.6)
Not tested Yes 87 (10.1)
Not tested No 141 (16.4)
Not tested Not tested 366 (42.7)
*

Laboratory findings consistent with possible ZIKV infection in a maternal specimen include (1) ZIKV RNA detected by PCR from any maternal serum, maternal urine, placenta, umbilical cord, or umbilical cord blood; (2) ZIKV IgM detected by serologic testing of maternal serum; and (3) ZIKV antigen detected by immunohistochemistry of placenta.

Laboratory findings consistent with possible ZIKV infection in a fetal/infant specimen include (1) ZIKV RNA detected by PCR from any fetal/infant specimen including serum, urine, CSF, and fetal/infant tissues; (2) ZIKV IgM detected by serologic testing of infant serum or CSF, and (3) ZIKV antigen detected by immunohistochemistry testing of fetal/infant tissue; confirmatory plaque reduction neutralization testing was not conducted.