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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Pediatr. 2020 May 13;222:112–119.e3. doi: 10.1016/j.jpeds.2020.02.023

Table III.

Likely etiology among cases of microcephaly and/or CNS defects, Colombia, September 2015-April 2017 (n = 858)

Etiologic classifications N (%)
Teratogenic—infectious 535 (62.4)
 ZIKV (n = 503)
  Strong evidence of congenital ZIKV (n = 124)
   ZIKV only (n = 117)
   ZIKV-STORCH coinfection (n = 7)
    Cytomegalovirus (n = 2)
    Toxoplasmosis (n = 5)
  Moderate evidence of congenital ZIKV (n = 232)
   ZIKV only (n = 224)
   ZIKV-STORCH coinfection (n = 8)
    Cytomegalovirus (n = 3)
    Toxoplasmosis (n = 4)
    Syphilis (n = 1)
  Limited evidence of congenital ZIKV (n = 147)
   ZIKV only (n = 141)
   ZIKV-STORCH coinfection (n = 6)
    Cytomegalovirus (n = 3)
    Toxoplasmosis (n = 2)
    Multiple STORCH (n = 1)
 STORCH (n = 32)
  Cytomegalovirus (n = 17)
  Toxoplasmosis (n = 10)
  Herpes simplex virus 1 or 2 (n = 2)
  STORCH-STORCH coinfection (n = 3)
Genetic 16 (1.9)
Multifactorial—neural tube defects 42 (4.9)
Unknown etiology 265 (30.9)
 Holoprosencephaly (n = 10)
 Multiple congenital anomalies (n = 38)
 Other unknown etiology (n = 217)