. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: J Pediatr. 2020 May 13;222:112–119.e3. doi: 10.1016/j.jpeds.2020.02.023

Table IV.

Strength of evidence for ZIKV etiology among cases of microcephaly and/or CNS defects potentially attributable to congenital ZIKV infection

Laboratory findings of possible ZIKV infection	Strength of evidence for ZIKV etiology	Birth defect group^* (number required)	ZIKV only (n)	ZIKV-STORCH coinfection (n)
Present	Strong	Group A (1 or more)	78	6
	Strong	Group B (2 or more)	39	1
	Moderate	Group B (only 1) AND Group C (1 or more)	72	6
	Moderate	Group C (2 or more)	10	2
	Limited	Group B (only 1)	5	0
	Limited	Group C (only 1)	19	6
Absent or unknown	Moderate	Group A (1 or more)	84	0
	Moderate	Group B (2 or more)	58	0
	Limited	Group B (only 1) AND Group C (1 or more)	97	0
	Limited	Group C (2 or more)	20	0

Figure 2 provides more information.