Table 1B.

Genes upregulated in LCs at 48 h PCS that are known to be involved in fibrosis in other systems, but are unreported, or only poorly described, in PCO.

Gene ID	Gene description	Fold change (FC) from WT 0 h to WT 48 h PCS in LCs	False discovery rate (FDR)	WT Mean RPKM 0 h	WT Mean RPKM 48 h	Reference
Arg1	Arginase	411	8.2E-81	0.38	185	[146]
Spp1	Osteopontin	126	9.2E-76	3	461	[147]
ECM1	extracellular matrix protein 1	85	8.9E-68	4	425	[148]
Lox	Lysyl oxidase	44	5.0E-78	0.47	24	[149]
Thbs1	Thrombospondin 1	23	9.4E-22	3	85	[62]
Tagln	Transgelin	17	5.2E-44	6	119	[150]
Postn	Periostin	5	3.8E-10	3	19	[151]
Osmr	Oncostatin M Receptor	5	9.4E-18	5.5	30	[152]
Ltbp1	Latent transforming growth factor beta binding protein 1	3	1.894E-07	30	98	[71]