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. 2020 Jun 12;23(7):101262. doi: 10.1016/j.isci.2020.101262

Figure 3.

Figure 3

Gene Expression (RPM, Reads per Million) Alteration in Response to PhenolaTi in MCF7 Cells at 54 μM

MCF7 were treated with 54 μM phenolaTi and sequenced in triplicates or duplicates after 0 (untreated), 3, 6, 15, 24, and 48 h. Expression analysis included CEL-seq2, Z-scoring, and hierarchical clustering. Roughly, the genes can be divided into five main clusters with distinct expression and significant biological functions. The biological functions of the genes were analyzed using GeneAnalytics, an integrative gene set analysis tool (Ben-Ari Fuchs et al., 2016). Blue, increased gene expression; red, decreased gene expression. Changes in expression of ER/hypoxia-related genes in response to phenolaTi in MCF7 cells.