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. 2020 Jun 28;10(6):e035087. doi: 10.1136/bmjopen-2019-035087

Table 2.

Prescribing issues identified by pharmacists during medication reviews (both chart based and face to face)

Indicators Cases
n (% of cases)
Addressed
n (% of cases)
Missing addressed data*
n (% of cases)
Potentially inappropriate prescribing
 Proton pump inhibitors 400 (44.2) 169 (47.9) 47 (11.8)
 Short-acting benzodiazepine 83 (9.2) 8 (11.4) 13 (15.7)
 Non-steroidal anti-inflammatories 75 (8.3) 27 (38.6) 5 (6.7)
 Duplicate therapeutic drug class 62 (6.8) 51 (87.9) 4 (6.5)
 Tricyclic antidepressants 46 (5.1) 9 (25.7) 11 (23.9)
 Long-acting benzodiazepine 28 (3.1) 2 (7.7) 2 (7.1)
 Incorrect instructions 27 (3.0) 24 (96.0) 2 (7.4)
 Opioids 26 (2.9) 9 (45.0) 6 (23.1)
 Diuretics 24 (2.7) 14 (63.6) 2 (8.3)
 Others 23 (2.5) 8 (53.3) 8 (34.8)
 Aspirin 20 (2.2) 6 (42.9) 6 (30.0)
 Direct oral anticoagulants 16 (1.8) 9 (69.2) 3 (18.8)
 Antipsychotics 13 (1.4) 6 (50.0) 1 (7.7)
 Systemic corticosteroids 13 (1.4) 2 (16.7) 1 (7.7)
 Prescribing omission 12 (1.3) 2 (33.3) 6 (50.0)
 Bladder antimuscarinics 9 (1.0) 6 (75.0) 1 (11.1)
 First generation antihistamines 8 (0.9) 2 (28.6) 1 (12.5)
 Digoxin 7 (0.8) 2 (40.0) 2 (28.6)
 Prochlorperazine or metoclopramide 7 (0.8) 3 (50.0) 1 (14.3)
 Methotrexate 4 (0.4) 1 (33.3) 1 (25.0)
 First-generation calcium channel blockers 2 (0.2) 2 (100.0) 0 (0.0)
 Theophylline 1 (0.1) 0 (0.0) 0 (0.0)
Overall 906 (100.0) 362 (46.2) 123 (13.6)
Deprescribing
 Other 64 (44.4) 37 (68.5) 10 (15.6)
 Z-drugs 39 (27.1) 5 (17.9) 11 (28.2)
 Antihistamines 12 (8.3) 6 (100.0) 6 (50.0)
 Betahistine 11 (7.6) 5 (62.5) 3 (27.3)
 Bisphosphonates 7 (4.9) 5 (71.4) 0 (0.0)
 Statins 6 (4.2) 5 (100.0) 1 (16.7)
 Antihyperglycaemics 5 (3.5) 4 (100.0) 1 (20.0)
Overall 144 (100.0) 67 (59.8) 32 (22.2)
Preferred drugs
 Statins 159 (33.8) 0 (0.0) 2 (1.3)
 Angiotensin II receptor blockers 76 (16.1) 0 (0.0) 0 (0.0)
 Proton pump inhibitors 75 (15.9) 18 (24.0) 0 (0.0)
 Selective serotonin reuptake inhibitors 55 (11.7) 0 (0.0) 0 (0.0)
 Beta-blockers 30 (6.4) 0 (0.0) 0 (0.0)
 Calcium channel blockers 24 (5.1) 0 (0.0) 0 (0.0)
 ACE inhibitors 15 (3.2) 0 (0.0) 0 (0.0)
 Inhalers 13 (2.8) 9 (75.0) 1 (7.7)
 Urology drugs 12 (2.6) 0 (0.0) 2 (16.7)
 Oral anticoagulants 10 (2.1) 0 (0.0) 0 (0.0)
 Serotonin norepinephrine reuptake inhibitors 2 (0.4) 0 (0.0) 0 (0.0)
Overall 471 (100.0) 27 (5.8) 5 (1.1)

*Missing addressed data refers to cases where the status of whether a prescribing issue has been addressed was not recorded.