Table 7.

A summary of side chain hydrogen bonding analysis between the two structural fragments generated by the hypothesized cleavage at the polybasic FCS of the S protein of SARS-CoV-2. In this table, the residue naming scheme is Chain ID_residue name_residue number, ∠ADH represents the angle formed by acceptor (A), donor (D) and hydrogen (H) (∠ADH). In this table, for residues A and B, one of them is to be located upstream (residue ID scriptsizeer than 681) of the polybasic FCS, while the other is to be located downstream (residue ID larger than 685) of the polybasic FCS.

PDB file name	Acceptor (A)	Donor (D)	Hydrogen (H)	D-A (Å)	H-A (Å)	∠ ADH ()
Model.pdb	OD2, B_ASP_737	NH1, A_ARG_319	HH12, A_ARG_319	2.74	1.78	15.71
Model.pdb	OD2, C_ASP_614	OG1, A_THR_859	HG1, A_THR_859	2.83	1.95	19.70
Model.pdb	OD2, A_ASP_614	OG1, B_THR_859	HG1, B_THR_859	2.98	2.16	26.02
Model.pdb	OD2, A_ASP_745	OG1, C_THR_549	HG1, C_THR_549	2.94	2.12	25.69
Model.pdb	OD2, A_ASP_848	NH2, C_ARG_646	HH22, C_ARG_646	2.63	1.79	27.55
Model.pdb	OG, C_SER_689	OG1, C_THR_676	HG1, C_THR_676	2.79	1.86	11.33
Model.pdb	OD1, B_ASP_614	NZ, C_LYS_854	HZ2, C_LYS_854	2.69	1.71	10.87