Table E2.
Demographic characteristics of clinical cohorts included in the IPD analysis
| Oxford, United Kingdom | Baltimore, Md | Montreal, Canada | Naples, Italy | Toronto, Canada | Total | |
|---|---|---|---|---|---|---|
| Study population, n | 226 | 295 | 35 | 868 | 440 | 1864 |
| Clinical demographics | ||||||
| Age, y | 65.5 (9.3) | 63.4 (10.0) | 66.2 (9.3) | 59.7 (8.2) | 60.8 (8.4) | 61.3 (9.0) |
| Males, % | 86.7 | 79.1 | 97.2 | 73.0 | 87.0 | 79.5 |
| BMI, kg/m2 | 28.1 ± 4.3 | 29.8 ± 6.2 | 28.2 ± 3.6 | 26.5 ± 3.2 | – | 27.3 (4.2) |
| Hypertension, % | 74.3 | 82.1 | 86.1 | 60.6 | 46.1 | 62.7 |
| Dyslipidemia, % | 89.8 | 83.7 | 94.4 | 57.7 | 68.5 | 68.9 |
| Diabetes, % | 23.9 | 34.8 | 27.8 | 15.9 | 26.1 | 22.5 |
| Previous MI, % | 47.8 | 40.5 | – | – | 46.1 | 48.7 |
| NYHA class, % | ||||||
| I/II | 44.9/43.1 | 88.5/3.4 | 32.8/50.0 | 38.4/47.1 | 48.0/37.8 | |
| III/IV | 10.2/1.8 | 5.4/2.7 | 11.8/5.9 | 11.1/3.5 | – | 10.7/3.5 |
| LVEF <50%, % | 14.3 | 0.3 | 20.6 | 35.7 | 51.4 | 31.0 |
| Creatinine, mg/dL | 0.93 (0.21) | 1.00 (0.24) | – | 1.05 (0.43) | 1.05 (0.210) | 1.03 (0.34) |
| Number of VD, % | ||||||
| 1 | 4.9 | 1.4 | 0.0 | 0.0 | 1.1 | |
| 2 | 22.1 | 14.9 | 14.3 | 22.9 | 19.0 | |
| 3 | 73.0 | 83.7 | 85.7 | 77.1 | 79.9 | |
| Operative characteristics, % | ||||||
| Urgent | 0.0 | 37.6 | 0.0 | – | 33.0 | 23.9 |
| On-pump | 18.6 | 97.6 | 88.9 | 5.9 | 100 | 45.8 |
| EVH | 86.3 | 53.4 | – | 0.0 | 0.0 | 21.0 |
| SVG number, % | ||||||
| 1 | 37.2 | 26.4 | 80.0 | 43.4 | 100.0 | 54.0 |
| 2 | 48.2 | 42.4 | 20.0 | 52.2 | 0.0 | 37.2 |
| ≥3 | 14.6 | 31.2 | 0.0 | 4.4 | 0.0 | 8.8 |
| Target vessel, % | ||||||
| Diagonal | 40.3 | 50.9 | 17.1 | 15.0 | – | 27.8 |
| LCx/OM | 61.1 | 69.2 | 22.9 | 52.9 | – | 52.6 |
| RCA | 69.9 | 66.1 | 60.0 | 94.6 | – | 74/8 |
| Complex grafts, % | 3.2 | – | 2.9 | 2.9 | – | 9.3 |
| Follow-up time, mo | <12 | 6 | 3 | 12 | 12 | <12 |
| Occlusion, % | 11.5 | 33.4 | 8.5 | 7.6 | 13.6 | 13.7 |
BMI, Body mass index; MI, myocardial infarction; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; VD, vessel disease; EVH, endoscopic vein harvesting; SVG, saphenous vein graft; LCx, left circumflex; OM, obtuse marginal; RCA, right coronary artery.